Depression – deficient feel-good chemicals, or brain inflammation?

Depression, which is very common, happens because we don’t have enough feel-good chemicals in our brains. It is all about neurotransmitters, the chemicals neurons use to talk to each other. Not enough of the right ones, then you are depressed. At least, that is what most doctors think, and what they tell their patients. Not University of Cambridge Professor Edward Bullmore. As Professor of Psychiatry, he has seen more mental illness than most, and he isn’t buying the chemicals theory. Depressed brains are inflamed, and he has just written a world wide best seller explaining why. Depression is common in people with inflammatory diseases, like arthritis, obesity (fat is inflammatory), and personal stress (inflammatory again). The science is still developing, but it appears that the best way to avoid depression is to keep your levels of inflammation well controlled. 

By | 2018-09-25T09:17:22+00:00 September 25th, 2018|Uncategorised|2 Comments

About the Author:

Dr Mulgan, co-founder and CEO of LifeGuard, witnesses the impacts of the western lifestyle on the ageing process through his practice as a GP. A significant part of Dr Mulgan’s practice sees him providing care to residents in retirement homes. It was his desire to place a fence at the top of the cliff, instead of an ambulance at the bottom, that lead to our flagship product, LifeGuard Essentials.


  1. Dennis Gale December 16, 2018 at 3:18 am - Reply


    Could not see how to obtain your book’The inflamed mind’ and what it costs plus postage for an inland location.

    Dennis W Gale.

    PS What do its contents say in synopsis form?

    • Mikael Aldridge December 20, 2018 at 4:53 am - Reply

      Dear Dennis, thanks for your interest! This is not actually our book. We regularly notice publications that cite the the role of inflammation in major diseases and tell our subscribers. This book is by a Professor of Psychiatry, Edward Bullmore, at Cambridge University. It lays out the evidence that depression is an inflammatory condition. Various online sellers have it currently, like

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