Some people will get frail when they are old, and some people won’t. Researchers at University Colledge London followed 6233 people from middle age (45 to 55) until they became elderly, to see who turned out to be robust in old age, and who turned out not to be. Their results have just been published in The Lancet, one of the world’s premier medical journals.
The researchers five predictive factors. The most important was physical inactivity. That was followed, in decreasing order of importance, by high levels of interleukin-6, obesity, high levels of C-reactive protein, and poor lung function (which means smoking). So what are interleukin-6 and C-reactive protein? They are molecules in your blood that measure inflammation. What does it all mean? The researchers conclude:
” Our findings suggest that interventions targeting physical activity, obesity, smoking, and low-grade inflammation in middle age might reduce …..later-life frailty.”
See it all here https://www.ncbi.nlm.nih.gov/pubmed/29908857